Adenocarcinomas can affect either the small intestine or the large intestine. They are usually quite rapidly growing tumours that often cause disease due to partial blockage of the intestine (loss of appetite, weight loss, vomiting and diarrhoea are the most common signs). Metastasis to local lymph nodes is common, and the tumours often invade the intestine quite extensively.

Surgical removal is the treatment of choice. Additional chemotherapy is used in some cases although the efficacy of this is uncertain. Long survival times can be achieved in some cases (with surgery alone) even where the tumour has already spread to local lymph nodes.


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